🩸 Duration of Antiplatelet Therapy After ACS in Patients on Long-Term Anticoagulation

This infographic summarizes expert guidance on managing antiplatelet therapy in patients with atrial fibrillation who are already on long-term oral anticoagulation and present with an acute coronary syndrome. It outlines how therapy should be tailored based on the timing of the acute event, whether PCI was performed, and the patient’s thrombotic and bleeding risks. Key takeaways include prioritizing DOAC over warfarin, favoring clopidogrel as the P2Y12 inhibitor, and minimizing triple therapy duration. The overall message: balance is key—optimize ischemic protection while reducing bleeding risk.

Created by Dr. Yong Hao Yeo

Reviewed by Dr. Claire Cambron

Reviewed by Dr. Sukriti Banthiya

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